Query by dubbiev: What is alopecia areata?
How does alopecia areata relate to lupus?
Response by Doctor Do.
History–A modest proportion of patients with alopecia areata have connective illnesses this sort of as systemic lupus erythematosus, discoid lupus erythematosus, rheumatoid arthritis, and scleroderma. Lupus erythematosus is related with a quantity of distinct varieties of alopecia, but the incidence of alopecia areata in lupus erythematosus has not been examined. OBSERVATIONS–Of our cohort of 39 clients with lupus erythematosus, alopecia areata designed in 10% (4 patients), in distinction to .42% of standard dermatologic clients. Biopsy specimens of alopecia areata lesions in each and every of our clients showed constant granular deposition of IgG at the dermoepidermal junction, a finding normally identified in only a minority of alopecia areata cases. Intralesional injections of corticosteroids ended up productive treatment. CONCLUSIONS–The incidence of alopecia areata in clients with lupus erythematosus is elevated. Recognition of this sort of alopecia allows for precise therapy with intralesional corticosteroids.
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